Sentry Matrix
Placental Tissue
Placental tissue, previously considered biologic waste following delivery, is a pristine newly formed extracellular matrix (ECM)
to protect and support fetal development. Therefore, this tissue represents an untainted extracellular matrix…essentially a
neomatrix.
Description Of Layers
The amnion membrane is a layer of placental tissue, and can be identified as the internal or fetus facing membrane. The
physical and biochemical properties of the the amnion is a thin, yet highly compact layer of extracellular matrix. Amnion
membrane is constituted of collagen fibers (predominantly Types I, Ill, IV and V), along with other ECM proteins (including
laminin, fibronectin, proteoglycans and hyaluronic acid). The elasticity and durability of the amnion layer allows it to conform
closely to wound surfaces while providing a protective barrier.
Safety
Donated tissues for Sentry™ products are collected from fully consented mothers undergoing full term c-sections.
Each donor is screened according to the strict standards required by the U.S. Food and Drug Administration and the
American Association of Tissue Banks. Further, Sentry™ Placental-Derived Allograft products undergo a validated
terminal sterilization process to help ensure these products are safe. All donated tissue is obtained in partnership
with FDA regulated and accredited recovery organizations. Additional details of screening procedures can be found
in the product package insert or Instructions for Use.
Product Overview & Usage Guide
Product Specifications
- 1. H. Niknejad, H. Peirovi, MJorjani, et al, “Properties of the Amniotic Membrane for Potential Use in Tissue Engineering”, EurCell Mater, vol. 15, pp 88-99, 2008.
- 2. A. Roy, M. Mantay, C. Brannan, and S. Gri iths, “Placental Tissues as Biomaterials in Regenerative Medicine”BioMed Research International, vol. 2022, pp. 1-26, 2022.
Need More Information?
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