Palisade Matrix
Placental Tissue
Placental tissue, previously considered biologic waste following delivery, is a pristine newly formed extracellular matrix
(ECM) to protect and support fetal development. Therefore, this tissue represents an untainted extracellular matrix……-
essentially a neomatrix.
Description Of Layers
Broadly, placental tissue includes an internal or fetus facing amnion and an external or maternal facing chorion. The
physical and biochemical properties of the two primary membranes are subtly different owing to the position they
occupy in the placenta. The amnion is a thinner yet more compact layer of extracellular matrix while the chorion is a
slightly thicker but less compact matrix. Both layers are constituted of collagen fibers (predominantly Types I, Ill, IV and
V), along with other ECM proteins (including laminin, fibronectin, proteoglycans and hyaluronic acid).
Safety
Donated tissues for Palisade™ products are collected from fully consented mothers undergoing full term
c-sections. Each donor is screened according to the strict standards required by the U.S. Food and Drug
Administration and the American Association of Tissue Banks. Further, Palisade™ Placental-Derived Allograft
products undergo a validated terminal sterilization process to help ensure these products are safe. All
donated tissue is obtained in partnership with FDA regulated and accredited recovery organizations.
Additional details of screening procedures can be found in the product package insert or Instructions for
Use.
Product Overview & Usage Guide
Product Specifications
- 1. H. Niknejad, H. Peirovi, M Jorjani, et al, "Properties of the Amniotic Membrane for Potential Use in Tissue Engineering", Eur Cell Mater, vol. 15, pp 88-99, 2008.
- 2.A. Roy, M. Mantay, C. Brannan, and S. Griffiths, "Placental Tissues as Biomaterials in Regenerative Medicine" BioMed Research International, vol. 2022, pp. 1-26, 2022.
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